Cardiometabolic risk reduction
Finding and lowering the risk that compounds quietly for decades: advanced lipids and particle testing, insulin resistance, inflammation, and metabolic health.
Precision Longevity Medicine · Miami & Telehealth
The annual physical that says you're fine is missing the years that matter.
Concierge, data driven longevity care from a Columbia and Cornell trained physician. We find the risks your standard checkup overlooks, from advanced cardiometabolic testing to hormones and metabolic health, and build a plan around your physiology, not the average.
Apply for Your Wellness Assessment
A physician led health audit, not a sales call.
Limited new patients each month.
Limited new patients each month.
- Columbia & Cornell Trained
- Board Certified in Emergency Medicine
- Precision Preventive Care
- 14+ Years of Clinical Experience
The gap in standard care
You are not fine.
You are not fine.
You are unmeasured.
Standard medicine waits for a number to break before it acts. By then the damage has a decades long head start. You feel it before the chart shows it. The afternoon crash, the lighter sleep, the weight that won't move, the recovery that takes longer than it used to.
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Brain fog and afternoon crashes are not just getting older.
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Stubborn weight is not a willpower problem. It is a metabolic signal.
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A normal cholesterol panel can look fine while the markers that predict real risk, and the hormones that drive how you feel, go unmeasured.
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Energy, sleep and mood are data you can read, and change.
Most programs hand you more to do. We start with a complete, measured picture of where your physiology actually stands today.
Limited to 10 new patients each month
This is not a sales call.
This is not a sales call.
It's a physician led health audit.
Healthspan by Design is a concierge practice. To protect the depth of care every patient receives, Dr. Joel takes on no more than ten new patients each month. The first step is a private call to see whether the Premier Wellness Assessment is right for you.
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Clarify your goal
The specific way you want to feel and function over the next ten, twenty, thirty years.
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Audit where you are now
Your history, current markers and the physiological bottlenecks quietly slowing you down.
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Map the path
If we're a fit, the exact assessment and plan that gets you there.
The call is the risk reversal. Even if we decide we're not a fit, you'll leave with a clear, honest read on where your health actually stands. No pressure, no obligation.
Apply for Your Wellness Assessment
A private, physician led call. Limited spots each month.
Your physician
Meet Dr. Joel Wussow
Columbia
Cornell
Board Certified · Emergency Medicine
Precision Preventive Care
Dr. Joel Wussow built Healthspan by Design on a simple conviction: the most powerful medicine is the kind that acts before you're sick. Trained at Columbia and Cornell and board certified, he practices precision, prevention first longevity medicine, reading the full picture of your physiology and translating it into decisions that compound over decades. He doesn't treat averages. He treats you: your data, your goals, your life.
He didn't build this practice out of theory. He built it out of his own bloodline. His grandfather had his first heart attack at 38, and went on to become one of the oldest heart transplant recipients in the country. For more than thirty years Dr. Joel did everything right: clean diet, ideal body weight, consistent training. His cholesterol stayed high anyway. The real driver was his ApoB, the particle count that actually pushes plaque into your arteries, and no standard checkup had ever flagged it. That's the gap he built Healthspan by Design to close: finding the risk that compounds quietly for years, long before it would ever surface.
Today the practice rests on lifestyle optimization, cardiometabolic risk reduction, and hormone optimization, delivered with physician oversight at every step.
Prevention is not the cautious choice. It is the most ambitious thing you can do for your health.Dr. Joel Wussow, MD
A named, sequenced framework
The Healthspan by Design Method
Four steps that turn scattered health data into a plan you can actually live, and sustain for decades.
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Measure
Your real baseline, not a guess.
The Premier Wellness Assessment. Comprehensive bloodwork across advanced cardiovascular and metabolic testing, hormone panels, inflammation and micronutrients, plus a full history.
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Map
A plan built by your physician.
Dr. Joel personally reviews every result and builds a prioritized, evidence based plan around your goals, never a generic protocol.
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Optimize
Move the markers that matter.
Targeted care across the five pillars of healthspan: Sleep, Nutrition, Movement, Stress & Mindfulness, and Medical Optimization. Physician oversight at every step.
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Sustain
Progress that becomes permanent.
Longitudinal care that adapts as your life and data change, so the gains hold for decades.
What's included
Inside the Premier Wellness Assessment
Your required first step, and the most complete picture of your health you've ever had.
Everything in your Assessment
Required first step- Comprehensive diagnostic bloodwork: over 100 biomarkers, including ApoB, Lp(a), full insulin resistance markers, a complete hormone panel, inflammatory markers, and micronutrient status.
- Your bloodwork is drawn at home. Our mobile phlebotomy service comes to you, so there is nothing to schedule around and no lab to sit in.
- Full medical history and lifestyle evaluation.
- A physician led review of every result, with Dr. Joel, not a portal.
- A personalized, prioritized optimization plan.
- Clear next steps and an ongoing care pathway.
- Everything explained in plain language: what your numbers mean, and what to do about them.
Optional add-ons
DEXA body composition
VO₂ max testing
Genetic testing
WHOOP integration
You'll understand not just what your numbers are, but exactly what to do about them, guided by a physician at every step.
Apply for Your Wellness Assessment
What we measure & move
Real markers. Measured. Moved.
The full Premier Wellness Assessment panel, organized by body system, under the three pillars of the practice.
Hormone optimization
Physician supervised evaluation and optimization of the hormones that drive energy, body composition, mood, and recovery, with defined protocols and oversight at every step.
Lifestyle optimization
Sleep, nutrition, movement, and stress, measured and tracked through wearable and body-composition data.
Cardiovascular
Total cholesterolLDL-CHDLTriglyceridesApoBLp(a)LDL particle sizehs-CRPHomocysteineand more
Metabolic health
Fasting glucoseHbA1cFasting insulinLPIR scoreLeptinUric acid
Hormones
Total testosteroneFree testosteroneSHBGDHEA-SEstradiolCortisolIGF-1PSAand more
Thyroid
TSHFree T3Free T4Thyroid antibodies (TPO, TgAb)
Nutrients, vitamins & minerals
Vitamin DVitamin B12FolateMagnesiumZincFerritinIronand more
Liver, kidney & electrolytes
ALTASTALPGGTCreatinineeGFRSodiumPotassiumand more
Blood count (CBC)
WBCRBCHemoglobinHematocritPlateletsFull differentialand more
Heavy metals
LeadMercury
Autoimmunity & inflammation
ANA screenRheumatoid factorhs-CRP
We present the systems we measure and move, never invented averages. Individual results vary.
What to Expect
METRICS THAT MOVE.
Every client starts with a measured baseline. This is where those numbers typically land six months later.
AEROBIC
VO2 Max
45+
from 36 ml/kg/min
HEART
Resting Heart Rate
Under 56
from 68 bpm
RECOVERY
Heart Rate Variability
58 to 80+
from 38 ms
REST
Sleep Efficiency
95%+
from 84%
STRENGTH
Lean Muscle
+6 to 10 lb
gained while losing fat
COMPOSITION
Body Fat
Under 15%
from 22%
LONGEVITY
Biological Age
6+ yrs
younger, measured by TruAge
HORMONES
Testosterone
780+
from 420 ng/dL, no TRT
Real Clients. Real Numbers.
5 PROOFS OF WHAT'S POSSIBLE.
From a 255% testosterone rebound to a physician returning to medical-school weight, these are KYP members who decided to know their physiology.
Hormones, rebuilt
Deficient
Low·Normal
Mid·Normal
Optimal
Body Fat
26.7% → 21.4%
Weight
232 → 220 lb
HbA1c
4.8% (optimal)
“After 6 months, I don’t need to make a conscious effort to live healthier - it’s just second nature now. Stable blood sugar throughout the day is probably the biggest thing. Gone were the energy crashes.”
Sleep, finally stable
Body Fat
23% → 16%
Weight
180 → 170 lb
Pull-ups
Noticeably Easier
“Man, I can’t tell you how happy I am with these changes - no more phone in bed, a dialed sleep setup, and the breathwork has been a game changer. I now wake up refreshed. I feel way lighter, and pull-ups feel easier.”
Recovery, compounded
Sleep
6h → 8h
Sleep Perf
95/100 avg
Lean Mass
+15 lb
“This is the best coaching I have received. I feel the improvement - we’re actually building together, I am not just taking a class. It was always a dream of mine to have a six pack, and now I understand exactly what my calories mean and how much to consume when I’m extra active.”
Sleep onset, collapsed
Body Fat
26% → 19.5%
Weight
−15 lb
Sleep Score
90% avg
“Even though I’m losing weight, I can still lift even more weights than before - my body composition has completely changed. I wanted clarity and a repeatable system, not more generic advice. Before, it would take me 45 minutes to fall asleep. Now it’s 5 to 10 minutes. That changes the quality of my whole next day.”
Cardiovascular age, reversed
Body Fat
24.7% → 19.7%
VO₂ Max
25 → 43
Fat Lost
30+ lb
“I have not been at this weight and BMI since I was probably in medical school or before. People I haven’t seen in a couple of months are all asking - wow, what happened to you? My VO₂ max started at 31. The highest we got was 43, and now I’m holding 42.4.”
More verified on Google
★★★★★ 5.0 average · 44 reviews
Beyond the 5 cases above, six more verified Google reviews from inside the Know Your Physio community.
JG
Jason Gustafson
“Know Your Physio has transformed the lives of many people, from local athletes to multi-billionaire entrepreneurs. Andres will change your life but you have to put in the work. This guy is absolutely brilliant and has cracked the code to feeling and looking incredible in every way.”
Read full review on GoogleKH
Kyle Hulbert
“These guys really KNOW PHYSIO! I’ve worked with Andres for about 8 months now and have seen massive improvements in lots of my health markers. The best improvements have been in my HRV and sleep scores. My body composition has also improved and I’ve put on over 25 lbs of muscle. Would highly recommend.”
Read full review on GoogleEK
Eduardo Krajewski
“Working with Know Your Physio and Andres Preschel has been truly life-changing for me and my family. He has also worked with my sons and has been instrumental in shaping their health habits at a young age. That, to me, is priceless. If you are looking for real, lasting change and not hype, I highly recommend Know Your Physio.”
Read full review on GoogleDK
David Krajewski
“Andres genuinely changed my life, which I don’t say lightly. I’ve worked with him two separate times now, at two different points of my life. Both times he helped me dive deep into what I needed most. Thanks to his help I sleep better, am incredibly more fit, and perform at a way higher level at work.”
Read full review on GoogleAG
Andrew Garcia
“I was born and raised in Miami. It’s extremely hard out here to find your people when you’re not interested in the bar scene. What makes what Andres built through Know Your Physio so special is a community of men who are serious about actually building something: their health, their fitness, their businesses, and real connections.”
Read full review on GoogleJR
Jorge Roman
“I’ve known Andres and the KYP community for several months now and I can say this is a group of people who take achieving excellence more seriously than any group I’ve ever been a part of. I wish I would have found them sooner.”
Read full review on Google
Founder and CEO @ Know Your Physio
Andrés Preschel, BSc, MSc(c)
Exercise Physiologist & Biomedical Neuroscientist
The Founder
Developed by
Andrés Preschel
Exercise Physiologist & Biomedical Neuroscientist
Andrés is not a "fitness influencer." He's an Applied Physiologist who understands the high-stakes demands of the 1%.
Dialing in his own physiology got him off a 10-year max-dose Adderall prescription after years of barely scraping through school with anorexia and anxiety. Adderall-free, he's earned full scholarships, run a lifestyle medicine internship under the University of Miami's Department of Kinesiology and Sport Sciences, co-authored a book about Hunger Hormones with a Harvard MD, and continues to speak on national live TV and stages around the world.
A decade in, he's rebuilt the physiology of WSOP Finalists, Le Mans Champions, Fortune 500 CEOs, ambitious entrepreneurs, and busy parents, so they don't have to chase degrees to fix themselves.
"Interoception, knowing what your body needs before a wearable tells you, is a human right. Learn it, and you unlock the clarity, energy, and longevity that data alone can never deliver."
READY TO GET VERIFIABLY ON TRACK TO LIVE BETTER AND LONGER?
You might be just ONE step away from results like these KYP clients.
TRUSTED BY THE .01%
From Fortune 500 CEOs to Grand Slam Champions. We don't ask for reviews; we deliver results that compel them.
"My energy levels have gone through the roof. I've gradually lost 10% of my bodyweight whilst keeping enough energy to increase muscle mass. We re-built my body... I just ran 16km at a pace I was doing 5km at a year ago."
Simon Denyer
Former CEO, DAZN
"TL/DR: Working with Andres is like having Tim Ferriss and Andrew Huberman in your back pocket AND on speed dial."
"The tools Andres offered me to get in touch with my own physiology and intuition transformed a simple fitness journey into an opportunity to reinvent myself."
Parker McCurley
Founder & CEO, Decent DAO
"I have really enjoyed our conversations. There are few people like you, and the hours we spent together are like gold."
Kevin Ryan
Founder of Business Insider
"Under his guidance, my sleep metrics went from good to absolutely elite. My average sleep percentage on Whoop climbed to near 100%, and I've maintained that level for six straight months now. A total game-changer for my recovery."
Kyle Hulbert
CEO & Founder at The Longevity Center
"Andres remained committed, consistent, and adaptable. His approach was structured and realistic, always keeping in mind what was sustainable for our lifestyle. His data-informed mindset helped us stay motivated and focused."
Joe Poulin
Board Member, Airbnb
"We were able to take a deep dive that gave me everything I needed to level up my health and performance beyond what I imagined was possible. I'm humbled by our experience working together."
Mickey Duek
WSOP Poker Champion
"Andres is genuinely tenacious about delivering personal satisfaction. His EQ makes the process feel natural, and the fact that he's done most of what he vouches for motivates you to walk the walk as well."
Ziv Tubin
VP VC Operations
"I had extreme food poisoning that affected me for over a year. With his help I restructured my gut biome... and gained muscle mass. I am now more competent, confident, and capable to handle health challenges myself."
Andrew Grace
Real Estate Investor
"In my journey, I've been fortunate to connect with Andres. He embodies wisdom and unwavering dedication, guiding me towards my health and fitness objectives. Here's to further achievements on the path to a healthier and more enriching life! Gracias Andres!"
Israel Zighelboim
Physician Executive | Wharton MBA | Gynecologic Oncologist
We're doing it again.
You might be just ONE step away from getting results like these KYP clients
Where this leads
The Assessment is step one.
The Assessment is step one.
Here's where it leads.
Premier Wellness Assessment
Your complete baseline and physician built plan. The required first step for every patient.
Annual Concierge Care
Quarterly physician consults, unlimited targeted labs, and prescription oversight throughout the year. Your longevity plan, kept on track.
Flagship Concierge
The highest touch tier. Dr. Joel as your personal physician, year round: direct access to his cell, sick care and travel medicine, the full testing suite (DEXA, VO₂ max, genetics, wearable tracking), and coordination with your other doctors. Optional elite health coaching available.
Most patients begin with the Assessment, then choose the level of ongoing care that fits their goals. We map the right path together on your call.
Limited patient panel
You could be one assessment
You could be one assessment
away from a different decade.
Limited new patients each month. Apply now to see if it's a fit.
Apply for Your Wellness Assessment
A private, physician led call. No pressure, no obligation.
Questions, answered
The friction a physician offer creates, removed.
Dr. Joel is a board certified physician. This is physician led preventive medical care, not coaching.
In person in Miami, and by telehealth in Florida, Texas, New York, and Arizona, where Dr. Joel is licensed.
We measure deeper, act earlier, and build a plan around you, with a physician who has the time to actually know your case.
Healthspan by Design is a cash pay concierge practice and does not bill insurance. This keeps your physician's time and attention on your care, not on coding. Labs can be drawn through our mobile phlebotomy service or brought from your own provider.
Your Assessment runs over your first few weeks: bloodwork, your physician review, and your plan. Ongoing care is then built around your schedule.
Pricing depends on the care level that fits you, which we determine together on your call. The Assessment is the entry point.
Then this is how you stay that way, and find the silent risks before they cost you years.
Yes, fully confidential and HIPAA compliant.
Apply
Apply for your Premier Wellness Assessment
A short application. If it's a fit, we send you a link to book your physician led call. Limited spots each month.
- Your information stays fully private and HIPAA compliant.
- This is an application, not a purchase. There is no charge to apply.
- A private, physician led call. No pressure, no obligation.
Ready to apply?
It takes about a minute. No charge, no obligation. If it's a fit, we send you a link to book your physician led call.
Your information stays fully private. This is an application, not a purchase. There is no charge to apply.